Injectables

 

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Skin Care

 

     Injectable filler materials can be used to fill contour depressions and fine lines as well as modifying facial shape.  Typical contour depressions include the nasolabial folds and marionette lines.  Lipstick bleed lines and crow's feet are examples of fine lines.  Lip and cheek augmentation are typical shape changes, which can be produced with injectable fillers.  Some injectable fillers are useful for one of the above categories and not others.  The average durability varies with different injectables.  All injectables carry risks of tissue reaction, infection, asymmetry, nodularity, and others.  Fortunately, with currently approved injectables these risks are uncommon.    A consultation can help determine the most appropriate modality to treat your concerns.  Alternatives to injectables include various surgical treatments such as autogenous fat transplantation (fat injection), and placement of Alloderm (freeze dried skin) and polytetrafluoroethylene (Softform, Gortex) as well as solid cheek and chin implants.  Various injectable materials are on the market in the United States.  In addition, many that are not approved for treatment  in the United States are in widespread use.  Some materials are being used for an application different from that for which they are approved -which is a widespread and legal part of the practice of medicine. Dr. Bass cautions that the effects of these materials in cosmetic applications is unknown .  Patient’s should be extremely concerned about placing unapproved materials in their faces, especially materials that are permanent, or non-biological.  See the News section for Dr. Bass' SnapReview on the subject of new injectables. 

Injectable Fillers

               Injectable Fillers are also recommended for wrinkles, crow's feet, and lipstick bleed lines

Restylane

    Restylane is a safe and natural cosmetic dermal filler that restores volume and fullness to the skin to correct facial wrinkles and folds, such as nasolabial folds. Restylane is FDA approved for use as a cosmetic filler.  This material is made from hyaluronate which is the predominate matrix material in our skin and connective tissues.  This is a very biocompatible material with little tissue reaction.  Because no anesthesia is mixed in with the material, nerve blocks must be used to allow comfortable injection.  The injection technique is significantly different from that used for collagen.  This material is commonly used for lipstick bleed lines, crow’s feet, lip augmentation and fill of nasolabial folds and marionette lines.  Average durability is generally considered to be 6 months.  

Radiesse

    Radiesse is a new long lasting injectable contouring agent which is FDA approved for cosmetic correction of facial contours such as nasolabial folds.  This provides  1-1.5 year durability for correction of depressions like nasolabial folds and marionette lines but is not used for fine lines like lipstick bleed lines or crow's feet.  Other areas of preferred application include cheek and chin contouring, nasal contouring, as well as correction of early aging changes in the pre-jowl sulcus before facialplasty is necessary.  The material is made of hydroxylapatite which is the mineral matrix occurring naturally in the body although the Radiesse material is made synthetically and is therefore sterile and not from an animal source. 

Fat Injection

    Fat injection, which is medically known as autogenous fat transplantation, utilizes your own fat, which is harvested with a needle and syringe to provide contour correction on the face and body.  This is a minor procedure which requires recovery.  Advantages include the use of your body’s own cells rather than a foreign material as well as the long duration (1-3 years or more) of the cells which survive in the new location.  Disadvantages include the recovery associated with the treatment and the variability in the amount of injected fat which does survive, often necessitating re-treatment one or more times over a year or two. 

Collagen

  Collagen is one of the oldest injectables in widespread use in the United States.  This is formulated from bovine collagen sold under the brand names Zyderm and Zyplast.  More recently synthetically formed human collagen (not from human donors) has been FDA approved under the brand names Cosmoplast and Cosmoderm.  Advantages include ease of injection, local anesthesia in the collagen making injection less uncomfortable, and good shape control. Collagen can be used for contour depressions, depressed scars, fine lines, and lip augmentation.   Disadvantages include the need for skin testing with bovine collagen, which delays the beginning of therapy and relatively short durability.  While the durability of collagen, or any injectable, will vary from patient to patient, Dr. Bass advises patients that they can likely expect no more than 3 months of correction. 

 

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